Compatibility guide for commonly used inhalation solutions and suspensions, 흡입제 적합성

 

 

Compatibility guide for commonly used inhalation solutions and suspensions

 

• Dark green shading with corresponding letter C: clinical studies confirming the stability and compatibility of the particular admixture.
• Light green shading with corresponding letter C: evidence from manufacturers’ reports confirming the stability and compatibility of a particular admixture.
• r. Red shading with corresponding letter X: evidence confirming or suggesting that a particular admixture is not compatible.
• Yellow shading with corresponding letters NI: insufficient evidence to evaluate compatibility and should be avoided unless future evidence becomes available.
• Blue shading with corresponding letters CD: conflicting data regarding compatibility of the combination.

 

 

주로 사용하는 흡입제들의 적합성

 

	상품명	벤토린	보스민	풀미코트	아벤트로	뮤코미스트(20%)
상품명	성분명	Salbutamol	Epinephrine	Budesonide	Ipratropium	Acetylcysteine
벤토린	Salbutamol		△	○	○	△
보스민	Epinephrine	△		△	△	△
풀미코트	Budesonide	○	△		○	○
아벤트로	Ipratropium	○	△	○		○
뮤코미스트(20%)	Acetylcysteine	△	△	○	○

 

 

Medication and Concentration	Recommended Inhaler Device	Comments
Albuterol (Nebulized solution)	Nebulizer	-
Epinephrine 1%	Nebulizer	jet nebulizer 사용 시 희석 필요
Budesonide(Nebulizer solution)	Nebulizer	-
Ipratropium bromide (Nebulizer solution)	Nebulizer	-
Acetylcysteine  100 mg/mL (10%), 200 mg/mL (20%)	Nebulizer	10% 희석하지 않고 사용 가능 20%는 NS or SW에 희석

 

reference:

1) Burchett, David K., et al. "Mixing and compatibility guide for commonly used aerosolized medications." American Journal of Health-System Pharmacy 67.3 (2010): 227-230.